| Date | Location | Result | |
| Nov 20, 2010 | Houston,TX | Texas Southern 20, Ark Pine Bluff 13 | Box score |
| Nov 11, 2010 | Houston,TX | Texas Southern 41, Grambling 34 | Box score |
| Nov 06, 2010 | Baton Rouge, LA | Texas Southern 54, Southern Jaguars 7 | Box score |
| Oct 30, 2010 | Houston, TX | Texas Southern 38, Mississippi Valley 7 | Box score |
| Oct 23, 2010 | Houston, TX | Texas Southern 21, Jackson State 18 | Box score |
| Oct 09, 2010 | Lorman, MS | Texas Southern 30, ALCORN 20 | Box score |
| Oct 02, 2010 | Montgomery, Ala. | Texas Southern 21, Alabama State Univ 7 | Box score |
| Sep 25, 2010 | Mobile, Alabama | Tuskegee 21, Texas Southern 14 | Box score |
| Sep 18, 2010 | Houston,TX | Texas Southern 32, Alabama A&M 9 | Box score |
| Sep 11, 2010 | East Hartford, Conn. | Connecticut 62, Texas Southern 3 | Box score |
| Sep 05, 2010 | Houston, Texas | PVAM 16, Texas Southern 14 | Box score |