| Date | Location | Result | |
| Nov 04, 2010 | Pine Bluff, Ark. | ALST 2, Texas Southern 1 | Box score |
| Oct 31, 2010 | Houston,TX | Texas Southern 4, Southern 0 | Box score |
| Oct 29, 2010 | Houston,TX | Jackson State 3, Texas Southern 2 | Box score |
| Oct 24, 2010 | Houston | Texas Southern 3, UH Victoria 2 | Box score |
| Oct 22, 2010 | Houston,TX | Texas Southern 5, Prairie View 3 | Box score |
| Oct 17, 2010 | Lorman, MS | Texas Southern 2, ALCORN 0 | Box score |
| Oct 15, 2010 | Itta Bena, Miss. | Miss. Valley State 4, Texas Southern 2 | Box score |
| Oct 10, 2010 | Grambling, LA | Texas Southern 5, Grambling State 0 | Box score |
| Oct 08, 2010 | Pine Bluff, Ark. | UAPB 3, Texas Southern 1 | Box score |
| Oct 03, 2010 | Houston, TX | Texas Southern 4, ALST 2 | Box score |
| Oct 01, 2010 | Houston, TX | AAMW 2, Texas Southern 1 | Box score |
| Sep 29, 2010 | Victoria, TX | UH Victoria 2, Texas Southern 1 | Box score |
| Sep 26, 2010 | Houston, TX | Texas Southern 3, Huston-Tillotson 0 | Box score |
| Sep 24, 2010 | Houston, TX | Houston Baptist 1, Texas Southern 0 | Box score |
| Sep 19, 2010 | Nacogdoches, Texas | Stephen F. Austin 7, Texas Southern 0 | Box score |
| Sep 17, 2010 | San Antonio, Texas | UTSA 7, Texas Southern 0 | Box score |
| Sep 12, 2010 | Houston, Texas | Houston 7, Texas Southern 0 | Box score |
| Sep 05, 2010 | Houston,TX | Sam Houston 2, Texas Southern 0 | Box score |
| Aug 22, 2010 | Fort Worth, Texas | TCU 7, Texas Southern 0 | Box score |
| Aug 20, 2010 | Denton, Texas | North Texas 8, Texas Southern 0 | Box score |