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Dr. Renard Thomas
Research Objective: The Effect
of Radiation And Simulated Microgravity on Genomic Stability
Determine the effects or radiation on
genomic stability under simulated microgravity environments. We hypothesize that
both acute and chronic radiation exposure will reduce the stability of the
genome by decreasing the DNA repair capacity of target cells (e.g. lymphocytes)
and that this loss may be amplified by microgravity exposure. We will also
investigate the mechanisms responsible for the attenuation of the DNA repair
capacity, as well as determine whether cell in simulated microgravity
environments are more susceptible to genotoxic compounds. (e.g. antimicrobial
agents).
NASA Research Center For Biotechnology and
Environmental Health
http://www.tsu.edu/academics/science/research/nasa.asp
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