Dr. Govindarajan Ramesh

 Research Objective: Studies with alpha-Tocopherol on Simulated Microgravity-Induced Oxidative Stress

Evidence in the literature suggests that microgravity induces inflammatory responses and modulates immune functions which may increase oxidative stress, resulting in biological damage to the human body. The molecular mechanisms underlying these effects are largely unknown, but it appears that the may be modulated by dietary factors. The microgravity simulator model, an apparatus called a Rotating Wall Vessel (RWV)    developed by NASA, is an ideal ground -based model system for examining the effects of microgravity on oxidative stress. The principal objective of this project is to study the role of alpha-tocopherol on microgravity-induced oxidative stress employing the RWV (in vitro) and anti-orthostatic tail suspension ( in vivo) models of simulated microgravity.

NASA Research Center For Biotechnology and Environmental Health

http://www.tsu.edu/academics/science/research/nasa.asp